Latex is a milky fluid derived from the lactiferous cells of the rubber tree, Hevea Brasiliens. It is composed primarily of cis 1,4-polyspherne, a benign organic polymer that confers most of the strength and elasticity of latex. It also contains a large variety of sugars, lipids, nucleic acids and highly allergenic proteins commonly known as allergens.
Allergy to natural rubber latex products is increasingly common. About the role of the four selected latex allergens, one may say that Hev b5 and Hev b6.02 are the most important allergens for adults as well as children and are likely to explain most of the allergenicity of latex products. Hev b1 and Hev b3 are major allergens for children with spina bifida and histories of multiple surgeries at an early age.